Diagnostics
Polygenic Score in Horses: When a Single Mutation is not Enough
Many people associate the term genetics with a simple and direct cause-and-effect relationship: one gene, one mutation, one trait. However, the genetic outcomes for many traits, such as performance, behavior, athleticism, disease susceptibility, and temperament, cannot be simplified in this way, as these traits are not defined by a single mutation but by hundreds to thousands of minor factors, each with its own tiny effect on the outcome. Individually, many of these variants have only a small effect, but when we look at them as a whole, they become more meaningful.
Genetic Health Panel Tests
If you’ve ever been around Paint or Quarter Horses, you have probably heard of health panel tests, more specifically, 5-, 6-, or 7-panel tests. A genetic health panel test is an umbrella term for multiple tests targeting several diseases, with the exact number of covered diseases varying between different panels. The respective associations overseeing these breeds may require these panel tests when registering horses for breeding, especially in the case of stallions.
When the Test Results are Negative but the Symptoms are Present
It may have happened to you, your friend, a family member, your dog or your horse. A genetic test was run in the hope of finding a reason behind your or their health problems, but the test results were negative. No questions were answered, and the patient was left undiagnosed. For now.